Since The Film Experience's famously favorite category is Best Actress, it's worth noting the year's wins in that regard thus far. I'm sure I'm missing foreign wins but I'm on tight deadlines. (Help me fill it out in the comments - previous error fixed. I type too fast. 75 wpm, bitches)

Sundance Festival Mo'Nique, Precious (Like Cannes, their acting prizes don't distinguish between lead and supporting)
Berlin Festival Birgit Minichmayr Alle Anderen (aka Everyone Else)
Cannes Festival Charlotte Gainsbourg, Antichrist
Amanda Awards (Norway) Ellen Dorrit Petersen, Iskyss
Venice Festival Ksenia Rappoport, La Doppia Ora
Sarajevo Festival Aggeliki Papoulia and Mary Tsoni, Dogtooth
Chicago Festival Giovanna Mezzogiorno, Vincere
Ophir Awards (Israel) Irit Kaplan, A Matter of Size

Rome Festival Helen Mirren, The Last Station
(and for the Italian Actress prize: Anita Kavros, Alaza La Testa)
Only one of these leading ladies is eligible in the Oscar race -- unless those VOD releases don't disqualify you and Gainsbourg is allowed to brutalize the gyno field -- and she'll most likely be nominated. Or she'll shoot you, obliterate you verbally, smash all your table ware. Don't mess with the Countess Sofya Andreyevna.